Author Archives: Anthony Dunn

Development of human lateral prefrontal sulcal morphology and its relation to reasoning performance

Research assistant Ethan Willbrand published a preprint identifying a relationship between developmental changes in the morphology of sulci in lateral prefrontal cortex (LPFC) and reasoning performance in childhood and adolescence. Analysis of both cross-sectional and longitudinal data sets revealed differences in cortical thickness between children (ages 6-11) and adolescents (ages 11-18). Further analysis revealed that longitudinal changes in cortical thickness of four rostral LPFC sulci predicted longitudinal changes in reasoning performance. Contrary to previous findings, these results suggest that sulci may flatten either after this time frame or over a longer longitudinal period of time than previously presented. Crucially, these results also suggest that longitudinal changes in the cortex within specific LPFC sulci are behaviorally meaningful—providing targeted structures, and areas of the cortex, for future neuroimaging studies examining the development of cognitive abilities.

You can read the paper here: https://cnl.berkeley.edu/papers/Willbrand_DEVPFC_Preprint_2022.pdf

Uncovering a tripartite landmark in posterior cingulate cortex

Research assistant Ethan Willbrand and PhD student Benjamin Parker of the Cognitive Neuroanatomy Lab published a new study uncovering a sulcus in posterior cingulate cortex (PCC) that is absent from neuroanatomical atlases. Variability in the location and morphology of this novel sulcus, termed the inframarginal sulcus (ifrms), is predictive of individual differences in macroanatomical and microstructural features of PCC, in addition to the location of functional regions of the lateral frontoparietal network implicated in cognitive control. The findings from this study provide support for Sanides’ classic hypothesis that tertiary sulci may serve as landmarks within association cortices.

You can read the paper here: Uncovering a tripartite landmark in posterior cingulate cortex | Science Advances

Presence or absence of a prefrontal sulcus is linked to reasoning performance during child development

A new study published by research assistant Ethan Willbrand and PhD student Willa Voorhies revealed that the presence or absence of the ventral component of the para-intermediate frontal sulcus (pimfs) is associated with reasoning performance in children. The findings from this study highlight the importance of considering individual differences in local morphology when exploring the neurodevelopmental basis of cognition.

You can read the paper here: Presence or absence of a prefrontal sulcus is linked to reasoning performance during child development | SpringerLink